British Air Force Typhoon FGR4s have operated alongside French warplanes in a coordinated attack on an underground arms cache in Syrian territory used by the Daesh militant organization, according to the UK's MoD.
The location, located using surveillance, was believed to be housing weapons and explosive materials, the release indicated, and was situated in mountains just to the north of Palmyra in central Syria.
"The RAF jets employed precision-guided Paveway IV munitions to strike a several approach shafts leading to the site... early reports suggest the strike was effective," the MoD said.
There was no sign of any civilian casualties in the strike conducted Saturday night and every plane involved returned to base without incident, the MoD added.
The Typhoon fighters were supported by a Voyager aerial refuelling aircraft.
The Islamic State group - alternatively referred to as the so-called Islamic State - enforced extremist governance over parts of Iraq and Syria until 2019.
"This action shows British leadership, and determination to operate in unison with allied nations, to eliminate any re-emergence of IS and their harmful and extremist ideologies in the region," Britain's Defence Chief the Defence Secretary said.
British military aircraft have performed surveillance missions over Syria to "prevent any attempted comeback" of IS following its defeat at the battle of Baghuz in the year 2019, the MoD reported.
"I must thank all the members of British forces who took part in this operation for their skill and their bravery," Healey said. "Including them were thousands of UK service members stationed over Christmas and New Year. This operation, to remove terrorist threats who pose a risk to our safety, highlights how our armed forces are always on standby, continuously, ensuring Britain's security within its borders and powerful internationally."
During December, the United States armed forces carried out what it described as a "massive strike" on Islamic State objectives in the country, subsequent to an attack resulted in the deaths of two US troops and a civilian linguist in the Palmyra area.
The United Nations reports Islamic State still maintains between 5,000 and 7,000 militants in Syria and Iraq.